England will face Andorra on Saturday without Arsenal forward Bukayo Saka, who has been omitted from the squad due to fitness concerns.
Head coach Thomas Tuchel indicated Saka had only one full training session this week.
Adding to the changes, Aston Villa striker Ollie Watkins has returned home with a minor injury.
The reason for Atletico Madrid midfielder Conor Gallagher’s exclusion remains undisclosed.
Saka, 23, missed three months last season with a hamstring injury and has yet to play under Tuchel.
England enters the World Cup qualifier unbeaten after wins against Latvia and Albania.
